GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs2294008 | 1 | rs2920294 | chr8:143765326 | LY6D | chr8:143866298-143868008:- | 0.22 | 4.81 | 2.21E-6 | Gastric adenocarcinoma (histologically verified);Non-cardia gastric cancer;Gastric cancer;Duodenal ulcer;Bladder cancer |
| BLCA | cis | rs2294008 | 1 | rs2920294 | chr8:143765326 | PSCA | chr8:143761875-143764142:+ | 0.52 | 16.1 | 6.5E-45 | Gastric adenocarcinoma (histologically verified);Non-cardia gastric cancer;Gastric cancer;Duodenal ulcer;Bladder cancer |
| BLCA | cis | rs2294008 | 1 | rs2920295 | chr8:143764937 | LY6D | chr8:143866298-143868008:- | 0.23 | 4.83 | 1.94E-6 | Gastric adenocarcinoma (histologically verified);Non-cardia gastric cancer;Gastric cancer;Duodenal ulcer;Bladder cancer |
| BLCA | cis | rs2294008 | 1 | rs2920295 | chr8:143764937 | PSCA | chr8:143761875-143764142:+ | 0.51 | 15.85 | 7.23E-44 | Gastric adenocarcinoma (histologically verified);Non-cardia gastric cancer;Gastric cancer;Duodenal ulcer;Bladder cancer |
| BLCA | cis | rs2294008 | 1 | rs2920296 | chr8:143763109 | LY6D | chr8:143866298-143868008:- | 0.22 | 4.79 | 2.43E-6 | Gastric adenocarcinoma (histologically verified);Non-cardia gastric cancer;Gastric cancer;Duodenal ulcer;Bladder cancer |
| BLCA | cis | rs2294008 | 1 | rs2920296 | chr8:143763109 | PSCA | chr8:143761875-143764142:+ | 0.51 | 15.95 | 2.78E-44 | Gastric adenocarcinoma (histologically verified);Non-cardia gastric cancer;Gastric cancer;Duodenal ulcer;Bladder cancer |
| BLCA | cis | rs2294008 | 1 | rs2920297 | chr8:143763083 | LY6D | chr8:143866298-143868008:- | 0.22 | 4.79 | 2.43E-6 | Gastric adenocarcinoma (histologically verified);Non-cardia gastric cancer;Gastric cancer;Duodenal ulcer;Bladder cancer |
| BLCA | cis | rs2294008 | 1 | rs2920297 | chr8:143763083 | PSCA | chr8:143761875-143764142:+ | 0.51 | 15.95 | 2.78E-44 | Gastric adenocarcinoma (histologically verified);Non-cardia gastric cancer;Gastric cancer;Duodenal ulcer;Bladder cancer |
| BLCA | cis | rs2294008 | 1 | rs2920298 | chr8:143763043 | LY6D | chr8:143866298-143868008:- | 0.22 | 4.79 | 2.43E-6 | Gastric adenocarcinoma (histologically verified);Non-cardia gastric cancer;Gastric cancer;Duodenal ulcer;Bladder cancer |
| BLCA | cis | rs2294008 | 1 | rs2920298 | chr8:143763043 | PSCA | chr8:143761875-143764142:+ | 0.51 | 15.95 | 2.78E-44 | Gastric adenocarcinoma (histologically verified);Non-cardia gastric cancer;Gastric cancer;Duodenal ulcer;Bladder cancer |
| BLCA | cis | rs2251844 | 1 | rs2920781 | chr15:43924682 | ADAL | chr15:43622872-43646094:+ | -0.39 | -4.43 | 1.23E-5 | Tumor biomarkers |
| BLCA | cis | rs2251844 | 1 | rs2920781 | chr15:43924682 | CATSPER2 | chr15:43922774-43959900:- | -0.36 | -5.27 | 2.33E-7 | Tumor biomarkers |
| BLCA | cis | rs17077154 | 1 | rs2922809 | chr8:6350464 | AGPAT5 | chr8:6565878-6619019:+ | 0.52 | 4.92 | 1.3E-6 | Cytomegalovirus antibody response |
| BLCA | cis | rs2251844 | 1 | rs2927072 | chr15:43922398 | ADAL | chr15:43622872-43646094:+ | -0.39 | -4.43 | 1.23E-5 | Tumor biomarkers |
| BLCA | cis | rs2251844 | 1 | rs2927072 | chr15:43922398 | CATSPER2 | chr15:43922774-43959900:- | -0.36 | -5.27 | 2.33E-7 | Tumor biomarkers |